Recombinant Prolactin
Recombinant Prolactin
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  • Recombinant Prolactin
  • Recombinant Prolactin

Recombinant Prolactin

货号(Catalog Number):

RP8062

价格:

¥ 2000

  • 规格
    • 100μg
数量
-
+

库存

1000

隐藏域元素占位

  • 产品描述
  • 产品数据

    产品描述(DESCRIPTION)

    Source 

    Human embryonic kidney 293 cells, HEK293
     Leu 29 - Cys 227, with a HIS tag  at the C-terminal
    Accession # Q5THQ0-1 

    Species

    Human

    质量属性(SPECIFICATIONS)

    SDS­PAGE 

    The protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) .

    Purity 

    >95% as determined by SDS-PAGE.

    Formulation 

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 5% trehalose and 
    0.01% Tween 80 were added as protectant before lyophilization

    保存与使用(PREPARATION AND STORAGE)

    Shipping 

    The product is shipped with dry ice.

    Reconstitution 

    Reconstitute at 100 μg/mL in sterile PBS 

    Storage

    For long term storage, the product should be stored at  lyophilized state at -20°C,avoid repeated freeze­thaw cycles.

    Stability

    >12 months, under -20°C conditions  before reconstitution.
    >6 months,  -80 °C under sterile conditions after reconstitution.

    背景介绍(BACKGROUND)

    Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds. Excessive secretion of prolactin - hyperprolactinemia - is a relative common disorder in humans. This condition has numerous causes, including prolactin-secreting tumors and therapy with certain drugs. The prolactin receptor (gene name PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Expression of the prolactin receptor is widespread. Each prolactin molecule is thought to bind two receptor molecules

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    4%-20% SDS-PAGE Result Recombinant Prolactin, 2ug reducing